AA_substitution(s) #Subset 1 A10G A129V A131S A150T A150W A152D A152T A156T A156V A15V A5G C138R C138Y C75K C75R C93R C93S C93Y D100G D102G D102N D127G D127V D33G D33V E118G E118K E118V E122G E122K E122L E122R E122S E122T E122W E12G E132D E132G E143G E145G E145K E145Q E145V E42G E42V E54G E78G E98G E99G F155S F155Y F58L F64I F64L F77S F82L G115E G34I G3R G55E G90R H20P H83R I107N I107T I107V I109L I109N I109R I109T I112A I112T I112V I116M I116T I116V I125F I125R I125T I125V I136T I45T I45V I4T I96L I96T I96V K101E K101R K110E K110R K110T K146E K146R K14R K153E K153R K154E K18R K48R K49E K49N K59E K59N K59R K65E K65N K65R K74E K74R K74S K76E K76R K76T L113Q L113V L114I L114S L119P L119R L120P L38R L38V L60P L63V L94P L94Q L97I L97S L9P M36T M39V M62I M62V N121D N121I N121S N121Y N124K N124R N124S N140D N140S N37S N85D P123E P157L P157S P28Q P32S P52L P73L P84L P84S P88L P88S Q111H Q111P Q117L Q117R Q126H Q126L Q126R Q130L Q130R Q151R R104G R104K R13G R141G R141I R141T R147G R8G S158A S158P S2L S2P S2T S70P S71P S71T S7C S89A S89L S89P S95P T108A T135A T135M T135S T29A T35A T51A T91A V142A V142E V148A V148D V148L V86A V86M V92A V92E W103R W16R W41R Y134F Y134N Y137C Y137S Y144C Y144H Y144S Y68C Y68H Y87C Y87H Y87N #Subset 2 A106I A106L A106M A106P A106T A106V A106Y A10S A10T A10V A129G A131G A131L A131P A131R A131T A131V A131Y A133M A133T A133V A150K A150S A150V A152G A152V A152Y A156G A15D A15P A26P A26V A44T A5T A5V C138F C138S C138W C43R C43S C43W C75G C75I C75N C75P C75Q C75S C75T C75W C93G C93W D100N D100Y D127A D127F D127N D127S D127Y D19G D19V D33E D33H D33N D66E D66G D66R D66V D67E D67L D67N D67Q D67T D67V D67W D67Y E118L E118N E118P E118S E118Y E122A E122C E122D E122F E122I E122Q E122V E12Q E132L E132S E132V E143I E143V E143Y E145F E54K E54V E78R E78T E78V E98K E98V E99D E99Q F155C F155L F22I F22L F22S F22Y F24L F24S F58S F64S F64V F77I F77L F77N F77P F77T F77V F82H F82K F82N F82R F82S G115K G115R G115S G115V G23D G23S G34C G34D G34M G34V G3E G47E G55N G55Q G55R G55S G56F G56S G90E G90W H20L H20R H83L H83M H83Q H83Y I107A I107C I107F I107L I107S I109E I109K I109S I109V I112M I112R I116K I116L I116R I125A I125L I125N I125S I125W I136F I136N I136Q I136V I45F I45H I4G I4L I4N I96C I96G I96S K101T K101Y K110A K110H K110L K110N K110V K146L K146N K14T K154A K154L K154Q K154R K154T K154V K18E K18L K18V K18Y K30R K48E K48T K49A K59I K65Q K74A K74D K74H K74M K74P K76D K76I K76N K76P K76S L113A L113C L113F L113I L113P L113R L113S L113T L114F L114G L114H L114K L114T L114Y L119A L119C L119G L119S L120D L120F L120H L120N L120Q L120S L38H L38I L38P L57F L57M L57S L60I L63F L63P L6H L81N L81S L81T L94K L94M L9H M1I M1T M36A M36I M36K M36L M36S M36V M39K M62R M62T M62W N121A N121C N121E N121F N121G N121K N121L N121P N121R N121T N124A N124C N124D N124H N124L N124P N140I N140T N31C N31D N31R N31S N31Y N37D N37K N37R N37W N37Y N40D N40S N40Y N85H N85K N85S N85Y P105E P105L P105R P105S P105T P105V P123F P123G P123K P123L P123S P123T P128L P128S P128T P157A P157H P157T P21A P21S P28C P28L P28S P32D P32L P32T P46L P46S P52D P52N P69K P69L P69R P69S P72C P72L P72S P72Y P73Q P73S P73T P79L P79S P79Y P80A P80S P88H Q111R Q111S Q111V Q117D Q117E Q117G Q117P Q11R Q126A Q126C Q126F Q126K Q126P Q126S Q126T Q130H Q130P Q130T Q139H Q139K Q139L Q139R Q151L Q151S R104M R104W R13W R141K R141S R141W R147L R147M R147N R147S R149G R149Q R149Y R17K R17S R61G R61P R61W S158L S2A S2R S71L S7G S7I S7N S7R S95F S95T T108I T108L T108S T108Y T29I T35P T35Y T51R T51S T91S V142F V142G V142H V142M V142P V142S V148F V148G V148I V25A V25L V25M V27A V27D V27H V86E V92L V92N W103C W103F W103G W103H W16D W16F W16I W16K W41L W53C W53G W53K W53R Y134C Y134H Y134R Y137F Y137H Y137N Y137W Y144D Y144F Y144T Y68D Y68F Y68K Y68N Y68Q Y68R Y87D #Subset 3 A106D,E118D A106G,I107N,L120P A106G,L120P,Q126L A106L,P123V A106L,Y134N A106Q,K153E A106R,V142A A106S,E122M A106S,E122V,Q151H A106T,A150L A106T,K110F A106V,I109T,P123T,E132G A106V,L119P,Y134H,A156V A106V,Q139R A106Y,E122V,D127S A106Y,N121S A10D,I107F A10D,L120V A10D,T91S,I107F,D127G A10G,A15E,M39V,L113I A10G,A15T A10G,A44G,I45V,K146E A10G,D100G A10G,D66N,S71P,A133T A10G,E145G A10G,E145V A10G,E54D A10G,F22S,I45F,D66E,E118D A10G,F58V,T91A,I109V A10G,H83L,T91I,E122D A10G,I107T A10G,K154E A10G,K30E,K49R,A150W A10G,K59E A10G,L120P,Y134S A10G,M62V,K74R A10G,P21T,L57M,F64S,S71P A10G,Q11R,P73S A10G,Q130R,Q151H A10G,R17G,S70P,S89P,I96V A10G,R61L,D66N,S71P,I107T,A133T A10G,S95P,A131V,Q151R A10G,T29A,C138R A10G,T35A,F58S,K101E,I107T A10G,V25A A10G,V25A,L63P,E99G A10N,N31D,G34R,M39T,K74Y,I96L,K101R,R104Q,V148L,K154L A10P,N40D A10S,D19E,L120A A10S,L38H,N85I,I125T A10S,L94P,L97S A10T,D67G,I96T,I116M,N124Y,Y134C A10T,K18E,L57S,L97S A10T,K18E,L97S,Y134H,V148D,F155S A10T,L114I,A133F,K146E A10T,L38P,C138Y A10T,P123F A10T,P123L A10T,P28T,C138Y,V142E A10T,P79I A10T,P88L A10T,R13G,A131T A10T,R13G,D33G A10T,T35V,K74V,E118F A10T,W16R,L97I,L120P A10V,D19G,N40S,F77L,S89P,W103C,K153E A10V,F82L,P157H A10V,N31D A10V,N31D,C93S A129T,A150T A131I,F155Y A131R,C138F A131V,F155Y A133F,V142A A133G,V142G A133T,K146R A150T,P157S A152D,K153R A152G,F155L A15C,W41D,W53G,M62V,Q111R A15E,K30R,P46M,P69Q,I96V,I109G,I125P,Y144A A15E,M36K,N37D,S95P,T135A A15E,M36K,R61Q,F77I,I125P A15E,P46M,P69Q,I96V,I109G,I125P,A129S,Y144A A15E,P46M,P69Q,I96V,I109G,I125P,Y144A A15E,P52Y A15G,W41D,W53G,M62V,Q111R A15I,G34T,K48N,T51H,H83R A15K,D67T,E122F,Y137M A15K,G34I,G50W,E78Q,E98P,A133T,K154L A15K,L63F,V148I A15L,G23D,W41R,F77Q,Q126R A15L,R141S A15P,I107T A15S,N121Q,E143N A15T,F77Y A15T,K76E A15T,K76I A15V,E42V,L63F,V86G A15V,E99G,L119P A15V,F77Y,Y144H A15V,G90R,L113V A15V,M39T A15V,M62L A15V,N37S,E42V,L97F,P105S,A150V A15V,P105C A15V,W103S,I107T A15W,D100G,Q126D A26E,I96Q,G115R A26G,A106T A26G,N31S,F77S,N124I,A150V,Q151R,K154M A26G,N31T,D67T,E132P A26G,R147S A26P,I109T A26P,T29A,E143G A26P,V27G,M36T,M39V,D66N,K101E,L119S,A152G A26R,P52R,P72E,H83Y,K110S,Q126S,V142L,A156M A26S,F64S,A156V A26S,F64S,Y134C,V142M A26S,K48E,K65N,C93S A26S,Q126P A26T,C75G,I112N,E122P,Y144C A26T,D67G,I112V A26T,E54G,T108A A26T,I109V A26T,I45V,D66R A26T,K59E,Q111R A26T,L63P A26V,E143G A26V,E98G,N124G A26V,F77S,P84T,E143G A26V,M39T,F82L,N85D,I112T,R149L A26V,M39T,S95Y,L113R,V142A,E145K A26V,R61S,K74R,I107M A44C,P105R,R141G A44D,L57S,I107T A44P,I107V,E118D,N124S,Q126R,A131S A44P,W103R A44S,F58S,V86M,R141G A44S,P52S,F64L,S158P A44S,V86A,K110R A44T,H83N A44T,I45V,P52R A44T,P52S,R104G A44T,P80R A44T,Y87N,V142A A44V,A131E A44V,E122V A44V,G115R A44V,K49N,A152G A44V,L81N,K110R,D127A,Y137A A44V,Q139R A44V,S71T A44V,Y134C A5D,F22K,P46L,E122V A5D,I136F,N140D,K153R A5G,A10G A5G,A10G,K154E A5G,A10G,M39T A5G,C93R A5G,D100N,F155L A5G,F155L A5G,F22Y,T51I A5G,G55R,P69L,D127G,I136V,K154R A5G,I107T,I136M A5G,I107T,I136M,R147G A5G,I136G A5G,I136V,K154R A5G,K14R,V92M,L113R A5G,K153E A5G,K30R,N124Y A5G,L9F,K48R,E78G,Y144D A5G,P21S,K48R A5G,Q130P,Y134C,R141A A5G,R104K A5G,R13W,W41R A5G,R17K A5G,R17K,D19G,L60C,P80T A5G,R17K,F22S,T35A,R104G A5G,T29A,L57V,N124S,P128S,Q151L A5G,T51A A5G,W53R,K59R,F64S,V86A,R104G,Y137H A5G,W53R,R149Q A5G,W53R,V86A A5G,W53R,V86A,K101R A5G,W53R,V92A,R149Q A5G,Y68C,E122L,C138W A5P,D66G,Y144H A5P,F24L,W53R,L119P,N121D A5P,K30N,K48R,D66Y,L81A,E98G,A106Y,A131N A5P,L38R,L81F,I96V,I107T,N121H A5P,L63F,C75V,R104W,Y144H A5P,N40S,E54K,Y137N A5P,P84T,E143V,Q151E A5S,K74R,A129T A5T,F64S,Y134C,V142M A5T,G50R,F82L A5T,K14I,E54D A5T,K14N,V92A,A129S A5T,K14R,K18R,F24S,M62I,I96T A5T,K153R A5T,L9F,H20R,M39K A5T,N37S,E132G,V142M A5T,N37S,V142M A5T,R61L,K65R A5T,V27A,T29S,M39L,N40D,E132G A5V,K48R,R61Q A5V,L113P,L120I,R147Y A5V,L120I,R141S A5V,M39T,W103R A5V,N37S,E99G,K154R A5V,R17G,E118G A5V,W41R,N121H C138R,R149Q C138R,V148A C138Y,N140R C43R,F58C,E132A,A133T C43R,F64S C43R,I96T C43R,K110E,I136V C43R,K48R,V86M,Q111L,I116V,Q117R C43R,K49I,D67N,P79R,E98V,F155L C43R,L114K,L120S,A150S C43R,N121V C43R,N140S C43R,P80S C43R,R104S,N121C,Y134H,V142A C43R,R147G C43R,R61G,Y134C,E143G C43R,S70P,P84R,I96T C43R,T51S C43S,D67W,P123E,R149T C43S,I116M,Y134N C43S,K65E,L119H C43S,L119M C43S,N85S,D100V C43S,P80L C43S,Q126K C43S,W53R C43S,Y134N C43S,Y68H,Q126P C43W,C75R C43W,I109F C43W,P73Q,C93R,R147W,A152G C43Y,E118G,K154R C43Y,F64S,P69S,F82S C43Y,K59R,D127G,Q139K C43Y,L63P,D67G,A129T C43Y,P72S,L94M,K110E C75A,E122G,D127G,R147K C75A,R147K C75D,Q111H C75D,T108P C75F,L114S,T135S C75F,N124L C75G,N121L,K146E C75H,A133T,E145G C75H,Q139R C75H,Q151L C75K,I107F C75L,L119F C75L,Q126A C75N,G115R C75P,K76T,L114R C75P,L97S C75Q,T135R C75R,E145G C75R,E98G,K110R,N124Y,K153R C75R,F82C C75R,I109V,V148A C75R,K76R,W103R,E122G C75R,L81S C75R,N124V C75R,P157L C75R,Q130R C75R,Q151A C75R,W103C C75S,A106V,I109T,N140D C75S,F82L,A106P,L120I C75S,K110P C75S,L119S C75S,N124S C75S,P157A C75T,E122G C75T,P88S,I136G C75T,T135E,N140H C75W,T108A C75Y,C93S,L113P C93G,I112F,I116K,E118W,P123N,V142A,V148G,K154E C93G,I112F,I116K,P123N,V142S,V148G,K154E C93G,K153R C93G,R104L C93R,E118G C93R,E118G,K154T C93R,I107V,E122G C93R,I107V,E122G,N140I C93R,I107V,E122G,V142A C93R,I136V C93R,K110R C93R,K146E C93R,P105G C93R,T108K C93S,I107V,Y144N,R147G,A152G C93S,I125T C93W,I116V C93W,P157L C93W,Q151R C93Y,A106T,A156V C93Y,Y137C D100G,C138S D100G,D102G,V148D,K154R D100G,D102N,T108I,E122I,R141S,K154E D100G,I136F D100G,K101E,P105S D100G,N121D,Y137F D100G,N124R D100V,A133G D100V,N121S D102G,E118D,P123Q,R141G,S158P D102G,I136V D102G,L120H D102S,Q117M D102V,A129D,C138R D102V,I136V D102V,L113P,N124R D127G,C138S,K153Q D127G,C138Y D127G,E132G D127G,I136T D127G,R141F D127G,Y144D D127I,A152R D127N,A129P,F155V D127N,K154M D127Q,R149L D127R,A156L D127V,K154M D127V,Y134C,Q139R D19A,E98G,Q117F,N121K,E143M D19A,F77C D19A,M36T,M62N D19A,N121R,R147S D19A,R104G D19E,G34V,G47K,F77Q,N85I,L120R,R147S D19E,Q117R,Y137C D19G,A131G D19G,A131V,Q151R D19G,A156V D19G,A44G,K110R,E143G D19G,A44T,H83N D19G,C75R,P84L,N124S D19G,C75R,P84L,N124S,F155L D19G,D127A D19G,D127G,R147S D19G,D33N,N85I,L97I D19G,E98G,T108I,Q126P D19G,E98K D19G,G47E,K48R D19G,H20R,N85S,R104G D19G,I96T,Q126H D19G,K101E D19G,K48R,W103R,N124F D19G,K74N,E122M D19G,L114S D19G,L38P,K146E D19G,L60C,M62L,P80I,P123R D19G,M36I,K110R,P123Q D19G,M36I,P123Q D19G,M39K,N85S,R104G,I107T D19G,M39V,V142E D19G,P157S D19G,P28L D19G,P28L,S158P D19G,Q139R,R141G D19G,R104G D19G,S95A D19G,T35A,K59R,K146R,A152T D19G,T35A,Y87H,I96T D19G,T91A,R104K D19G,V92A D19G,W53G D19G,Y87H,T91S,I96T D19N,D33F,F58R,C75V,Q111V,N121D,E122G,Q151L D19N,K101R,Y144C D19N,M62V,E78V D19N,N37Y,K101R,Y144C D19N,Q130L,A150L D19N,V25L,I45V D19V,G55Q,Q117M D19V,K110E,Q126S D19V,L81S,C93R D19Y,G23C D19Y,G34S,P52N,P72Q,P105D,K110R,I112T,L113P,L119H,N140S,K153G D19Y,G34S,P52N,P72Q,P105D,L113P,N140S,K153G D33A,L97S,Y137F D33E,G115E D33E,S95P,Q130R D33E,V142A D33E,Y134H D33F,T108R,N124R D33G,C93G D33G,D127G D33G,D66E,P72S,I96G,P123S D33G,D66G,E143Q D33G,E118L,R147G D33G,E143G,Q151H D33G,I109T D33G,K153E D33G,L63P,S95P,E122G,D127G D33G,M39V,N124Y,A150T D33G,M39V,W103R,N124Y,A150T,F155L D33G,N121Y,A156I D33G,P105Q,Q151R D33G,P123L D33G,P123S,Q130R D33G,R104N D33G,R147G D33G,R147G,K153E D33G,T51N,P52L,P69S,N85Y,T135R,Y144C,F155C D33H,T35A,E122D,Q130R D33I,I125A,V142E D33I,Q126L,A133T D33N,C75R,S95P,E145G D33N,R61P D33N,S158P D33N,S95P D33Q,R61G,T135A D33S,F77H,I112M D33S,R61Q,E143V D33V,C75G,Q111V,E145G,Q151L D33V,L60H,N121I D33V,M62T,N121T D33V,T51A,L81Y,S95Y,C138R D33W,F77P,K153Y D33Y,C75R,W103C D33Y,E42G,K110R,L113V D33Y,P128S D33Y,Q151R D66A,Y87D,I116W,E143V,F155Y D66C,P79L,L113P,I125T,E132G D66E,I107P,N121S D66E,I107V,E122D D66E,K110N,E122Y,Y137P D66E,R104G,L119T D66E,V92M D66F,I109G,E118V,I136V D66G,C75Y,K76E D66G,E98D,R104K,L120P D66G,E98D,R104K,P105A,L120P,N140D D66G,H83L,K154R D66G,K76E D66G,L94P D66G,L94P,I116V,Q130L D66G,L97S,I125T D66G,L97S,Q139R D66G,P73S,L97S,I125T D66G,Q111L D66G,R104C,A152V D66G,R141G,Q151R D66G,S158P D66G,T135A D66G,Y144H D66H,A106T D66H,N85S,L119G,Q126R D66I,D127C,Y134C D66I,L81R D66K,E122D D66K,Q130L D66L,L114D,I125T,K154E 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E12W,T29P,K48R,K59N,L81T,I96T E132F,C138S,K153R E132G,I136T E132Q,C138Y E132V,C138Y E132V,Y144C E143G,A152G E143G,K153E E143G,Q151V E143G,V148G E145G,R147N E42A,C75R E42A,I136T,E145G E42D,L120S,V142Y E42G,A106V E42G,A44V,K59N,N124K,E143H E42G,C75R,E98G,Q126H,N140S E42G,D102Y E42G,D66P,N121M E42G,D67Y,K153R E42G,E145V,F155I E42G,E78G,E99G E42G,E78G,I107N,N124S E42G,E98G,L119R E42G,I116V E42G,K110R,T135A E42G,K49E,F64S,I109V,T135M E42G,K49R,S71L,P72L,C138G E42G,L113V E42G,L114A E42G,L114S,N124S,E143V E42G,L114S,N124S,Q126R,E143V E42G,P84Q E42G,P84Q,E122G E42G,R61W,L63F,E78D E42G,W103E E42G,W53R,P88S E42G,Y144H E42G,Y87F,E99G E42H,L81H,I136T E42K,I45M,L81Y E42K,L113H E42Q,I136M,Q139K,R141S E42Q,I45F,E122V E42S,K74R,I107A,Q130T,R149G E42V,E54G E42V,L97F,P105S E42V,S95A E42W,C75E,N124V E54A,K110A,T135V E54A,T108P,A156V E54D,F58Y,C93R,E98G E54D,F77S E54G,C75R E54G,C75Y,A129V,E145I E54G,C93S E54G,D66I,S89P,A152K E54G,D67I,P123S E54G,E145K E54G,E78G,N85D,S95P E54G,F64L,Q151R E54G,I112R E54G,K110N,Q126K E54G,K65R E54G,K74E,P79L,N85Y,Q126K,E145K E54G,K76D,K101R E54G,K76N,T91A,L94Q,Y134N,E143V E54G,K76R E54G,L63V,D67A,P73S,E99G,I116V,Y137C E54G,N140S E54G,P79L,E145K E54G,Q151R E54G,R141Y E54G,T91A,Y134N E54G,V86A,I116V E54K,E122G E54K,F64S,F82I,I125T,Y144C E54K,F82I,I125T E54K,L63P,D67A,Q126L E54K,Q126S E54P,F82S,Y137C E54V,G115E,R141G E54V,I116V,Y134N E54V,K74S E54V,L60P,P69R,Q130L,A131V E54V,M62G,I109M,Y144C E54V,Q126R E78G,A106T E78G,C138Y E78G,E132G E78G,I116M,Q139R E78G,I96V,P123V,Q130H E78G,K146R,V148D E78G,Q111K,Y134P E78G,V148A E78K,H83Y,D127E E78K,H83Y,D127G,C138Y E78K,R147W E78R,I107L E78R,L113P,K154R E78R,Q130R,V148F E78T,K110A,Q126S E78V,E143G E78V,H83Q,L119C E78V,L113Q,R141K E78V,Y144S,P157S E78W,N121L E98A,Q126R,Q130R,K153M E98D,R141G E98G,F155L E98G,N140I E98G,Q126F,Y137F,V142T E98G,T108A,L119P E98G,T108A,L119P,N121D E98K,Q111M E98K,Q111M,I112V E98K,Q117N E98V,I107L,R147V E99G,K146R E99G,K153Q E99G,L119F E99G,L119F,F155L E99G,N140D E99G,Q130P,V148A 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F24I,I107F,I136T F24I,I45F,W53R,P69S,P80S,Y87D,A129V F24I,K110E F24I,K74R F24I,P80L,V92A F24I,S71P,E118D,N124S,Q126R F24I,V148A F24I,Y87D F24I,Y87D,L114S F24K,K59N F24L,A26S,K48E,K65N,C93S F24L,D33Y,W41C,S95P,F155L F24L,D66T,R147Q F24L,F64L F24L,F64S,N121Y,K154Q F24L,I45T,K74E F24L,I45T,K74E,N121Y F24L,K101R F24L,K101R,N121H,A133V F24L,K154E F24L,K48E,I136V F24L,K65E,N140D F24L,K65R,Y68C,I96T F24L,K74E F24L,N124S F24L,N37S,M39V,K49E,H83R,C93R,I96V,I107V,I125V,R149G F24L,N37S,M39V,K49E,H83R,C93R,I96V,I107V,I125V,T135S,R149G F24L,N37S,M62V,R104W F24L,N37W,E118N F24L,N40S,E118G F24L,Q139L F24L,R104G,K146E F24L,R104G,Y137H,C138R,K146E F24L,R61Q,K146R,K153R F24L,T135M F24L,T35P,Y87C,L113C F24L,T51S,I109V,I116M F24L,T51S,I109V,I116M,K146E F24L,V27A F24L,W103C,Q139H F24L,W103R F24L,Y68N,R104K F24N,N40Y,L120M F24S,A106S,E118K,V148A F24S,A26G,E99G,Q126H F24S,A26S,K59N,F64L,F82L,E122M,T135P F24S,D127G,A131G F24S,D33G,E54L,L63P,K74S,E122T,Y137R F24S,E78T,R141V F24S,F58S,L81P F24S,G56R,Y87C F24S,I112N F24S,I125T,K146R F24S,K146E F24S,K48R,C75Q,H83L,Y87D,I112R,V148Y F24S,K49R,Y134F F24S,K59I,L94R F24S,L114F,G115R F24S,L63P,V142L F24S,L97F F24S,N40Y,P84S F24S,P79D F24S,T35A F24S,T35A,N40D,E118V F24Y,E54G,N121S,E132G,A152W F24Y,E54G,N124D,E132G F24Y,G34A,L119G F24Y,H83M,N85H,N121A F24Y,K48E,E54G,N124D,E132G F24Y,K59R,I112T,N124S,Y134N F24Y,T35P,G55P,D66S,D102G,Q111H,L120V,Y134A F58C,K59N F58I,Y87C F58L,A131V F58L,A131Y F58L,A133T F58L,A156V F58L,E145G,K153M F58L,E78G,Y137C F58L,E99G,I109T F58L,F155S F58L,F64Y F58L,F77L,V86A,K101E,S158P F58L,F82R F58L,I116K,D127M F58L,K59R,F77L,Q151R F58L,K76A F58L,K76R,V86A,S158P F58L,L63P,N124I F58L,M62V,D67T,K110I,I116A F58L,M62V,K110I F58L,P72R,I109T,F155S F58L,R147S F58L,S70P,K146R F58L,V86A F58L,V92M F58L,Y87F,L114F,A131V F58P,P105L F58R,I96T,N121S,P123I F58S,A133K F58S,F64L,Q126R F58S,K59E F58S,K65E,S158L F58S,K74E,E118S,A152V F58S,L63H,C75R F58S,M62R,C75S F58S,M62V,Q126L,A133T,T135S F58S,N121P F58S,P80A,P88L,S95P F58S,S95T,A133G 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M62I,S70K,N121V M62K,D66G,S70P,K74R,R104K M62K,E78G,Q139H M62K,E78G,T91I,S158L M62K,I116T,A133D M62K,K74R M62K,K76M,A131R,T135M M62K,K76M,L120E,T135M M62K,L120E,Y134H,T135M M62K,Q139H M62L,D127G M62L,P123R,A131P M62L,R104A,P123R,A131P M62Q,I136V M62Q,K74T,Q111P,I136V,N140I,P157F M62Q,N121G M62T,A156V M62T,D127G,R141G M62T,F77I,D127G,R141G,K146R M62T,F77L,G90V,Y137F,K154R M62T,I107N M62T,I136S M62T,I96T,D100G,E145A M62T,K101R M62T,K74E,E122D,V142M M62T,L63R,F82S,Q130R,I136T,A156T M62T,L63R,F82S,Q130R,I136T,K153E M62T,L94P,K110R M62T,L97S,D102Y,C138W M62T,S70L,T135A,I136T M62V,C138R M62V,C75S,V86A,P88L,K110P M62V,D127G M62V,G90R,K110E,I112V M62V,I109T,L113F,Y134H,S158P M62V,I125T,C138R M62V,K110E,I112V M62V,K153M M62V,K74R,L113Q,D127G M62V,K76R,E132K,K153M M62V,L119V M62V,S71P,I107F M62V,T135S M62V,T91A,I109F M62V,T91S M62W,D102E N121D,P123S,Y144C N121E,R141G N121F,R149Q N121G,F155L N121I,P157S N121L,A131T,Y137C N121S,R147K,K154R N121T,E145R N121Y,R147G N124A,E145K N124D,R141K 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