Substituted-residue	Prediction(high-pyridoxine-conc.)	Standard-deviation	Prediction(low-pyridoxine-conc.)	Standard-deviation
H65R	*	*	*	*
P70L	*	*	*	*
P78R	*	*	*	*
G85R	*	*	*	*
T87N	*	*	*	*
P88S	*	*	*	*
L101P	*	*	*	*
K102Q	*	*	*	*
A69P	*	*	*	*
K102N	*	*	*	*
C109R	*	*	*	*
A114V	*	*	*	*
G116R	*	*	*	*
R121C	*	*	*	*
R121H	*	*	*	*
R121L	*	*	*	*
M126V	*	*	*	*
E128D	*	*	*	*
E131D	*	*	*	*
G139R	*	*	*	*
I143M	*	*	*	*
E144K	*	*	*	*
P145L	*	*	*	*
G148R	*	*	*	*
G151R	*	*	*	*
I152M	*	*	*	*
G153R	*	*	*	*
L154Q	*	*	*	*
A155T	*	*	*	*
A155V	*	*	*	*
A158V	*	*	*	*
C165Y	*	*	*	*
V168M	*	*	*	*
E176K	*	*	*	*
V180A	*	*	*	*
T191M	*	*	*	*
D198V	*	*	*	*
R224H	*	*	*	*
A226T	*	*	*	*
N228S	*	*	*	*
N228K	*	*	*	*
D234N	*	*	*	*
E239K	*	*	*	*
T257M	*	*	*	*
G259S	*	*	*	*
T262M	*	*	*	*
R266G	*	*	*	*
R266K	*	*	*	*
C275Y	*	*	*	*
I278T	*	*	*	*
A288T	*	*	*	*
A288P	*	*	*	*
P290L	*	*	*	*
E302K	*	*	*	*
G307S	*	*	*	*
V320A	*	*	*	*
A331E	*	*	*	*
A331V	*	*	*	*
R336H	*	*	*	*
G347S	*	*	*	*
S349N	*	*	*	*
S352N	*	*	*	*
T353M	*	*	*	*
V354M	*	*	*	*
A355P	*	*	*	*
A361T	*	*	*	*
R369C	*	*	*	*
R369H	*	*	*	*
R369P	*	*	*	*
C370Y	*	*	*	*
V371M	*	*	*	*
D376N	*	*	*	*
R379W	*	*	*	*
K384E	*	*	*	*
K384N	*	*	*	*
M391I	*	*	*	*
P422L	*	*	*	*
T434N	*	*	*	*
I435T	*	*	*	*
R439Q	*	*	*	*
D444N	*	*	*	*
L456P	*	*	*	*
S466L	*	*	*	*
Q526K	*	*	*	*