401.864.8839
cash21@ccs.neu.edu                                                      .pdf version
828 Huntington Ave.
Boston, MA 02115

Education
Northeastern University, Boston, MA                                                                  Sept. 2003 - Present

  • Candidate for a Bachelor of Science in Computer Science and Biology
  • GPA: 3.61/4.00, Outstanding Co-op Student Award, CRA Outstanding Undergraduate Honorable Mention, Dean's Scholarship recipient, Member of UPE Computer Science Honors Society, Leader of CISters - NU Women's Computing Group

    • Toll Gate High School, Warwick, RI                                                                    Sept. 1999 - 2003

  • Honors: National Honor Society, RI Honor Society, National Spanish Honor Society, Quill & Scroll Writing Award
  • Activities: Varsity Basketball, Varsity Field Hockey, Yearbook Editor, Math Team, Student Committee, Technology Improvement Committee

    • Work Experience
    Bioinformatics Analyst - Dana-Farber Cancer Institute, Cancer Biology, Boston, MA 2007 - Present

  • Designed and currently maintain a Rich Internet Application (eNotebook publication pending), which enables scientists to describe, track and analyze their experiments by enhancing the data capture process
  • Enable machine-learning and expert human analysis of protein identification, modification and interaction
  • Developed a protein-protein interactor component, which is linked to a local instance of the Human Protein Reference Database (HPRD)
  • Maintain an Oracle 10g database linked to a custom automated data analysis pipeline, which monitors .RAW files being acquired from several mass spectrometers

    • Bioinformatics Researcher - Children's Hospital Informatics Program, Boston, MA   2006 - Present

  • Analyzed genetic data involving Huntington's disease and Asthmatic patients using methods such as Principal Components Analysis, Hierarchical Clustering, t-tests, SAM (Significance Analysis of Microarrays), and various filtering/normalization procedures
  • Applied Gene Set Enrichment Analysis (GSEA) to a time series of mouse cerebellum developmental data to discover metabolic pathways that are regulated during specific stages of brain development - currently continuing this research
  • Utilized GSEA to identify underlying mechanisms common to both human medulloblastoma and specific stages of cerebellar development
  • Attended the 2006 NIH Roadmap Biomedical Computing Conference in Bethesda, MD to present results obtained from analyzing Huntington's disease samples
  • Derived algorithms to analyze complex diseases such as Autism and Asthma using linkage peak data in conjunction with GSEA
  • Attended a one day "Analysis of Microarray Data" workshop hosted by John Quackenbush
  • Participated in weekly meetings and journal clubs in which recent publications were discussed and reviewed
  • Participated in the the Harvard-MIT Division of Health Sciences and Technology Summar Scholars program, which teaches undergrads about the latest tools and techniques for bioinformatics research

    • Applications Analyst - Harvard Partners Center for Genetics and Genomics, Cambridge, MA   2005 - 2006

  • Provided analytical, user adoption, and QA support throughout software development life cycle for the following projects: Variant Database, DNA Microarray & Research Sequencing, GIGPAD
  • Performed usability assessment on DNA Microarray Laboratory Information Management Systems (LIMS) and Variant Database
  • Created user documentation for the following systems: Variant Database, GIGPAD, FIND
  • Defined requirements for variant nomenclature to enable structured reporting of point mutations to the electronic medical record (EMR)
  • Co-designed baseline aCGH (array comparative genome hybridization) structured report format
  • Participated in baseline XML object model design for messaging genetic variant results to enterprise systems

    • Professor's Assistant/Researcher - Northeastern University - Boston, MA                       2004 - 2005

  • Researched tools to be used in the development of an online portfolio system for students
  • Discussed project plans with co-op advisors and professors for the portfolio system
  • Co-authored "Calculator Problem and the Design Recipe," published in ACM SIGPLAN Notices, Volume 40, Issue 3 (March 2005).
  • Presented student poster and co-led workshop entitled "Focus on the Design of Classes in OO Programming Courses" at the Consortium for Computing Sciences in Colleges - Northeastern Region 2005
  • Analyzed diagrams from open access biology publications on BioMed Central for CCIS Research

    • Computer and Scientific Skills
    Languages: R, Java, C++, C, Actionscript, HTML, PHP, Python, Perl, SQL, XML, Scheme, JSP, SQL
    Systems: Windows (9x, NT, 2000, Me, XP), DOS, Unix, Linux, OS X
    IDEs: Eclipse, Frontpage, Adobe Flex Builder, Macromedia Flash, Borland Builder, TOAD
    Technologies: Apache HTTP Server, Oracle, OpenSSL, CVS;Subversion, MySQL
    Office Applications: Microsoft Office (Excel, Powerpoint, Word), Adobe Photoshop 7.0
    Scientific Applications: LIMS (Laboratory Information Management Systems), Bioconductor, TIGR MEV, Mascot
    Clinical Applications: Tamtron PowerPath (diagnostic reporting system)
    Laboratory Skills: basic skills in laboratory technique, statistics, histograms, microbiology, microscopy, experimental design, gel electrophoresis
    Functional Skills: communication (verbal, written and graphical), able to work independently and in cross-functional team environment, prolific results-driven work style, multi-tasking and task management


    References available upon request